Oral history of British science

Klug, Aaron (Part 14 of 31). National Life Stories Collection: General

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  • Subjects

    Biophysics; Chemistry

  • Recording date

    2002-10-29, 2002-11-03, 2002-11-20, 2002-11-27

  • Recording locations

    MRC Laboratory of Molecular Biology, Cambridge

  • Interviewees

    Klug, Aaron, 1926-, (speaker, male)

  • Interviewers

    Thompson, Katherine (speaker, female)

  • Abstract

    AK talks about his circle of friends in London, mentions book reviews he wrote, enjoyed being a father. His wife taught at nursery school in St. John's Wood. Story of his son's reply to the bragging of other children. Meeting Rosalind was turning point in his life. Back to Cambridge. About meeting in Coldspring Harbour, work with Caspar, explains problem they worked on. Publication of joint paper. Also work on electron microscopy - explains work in those early 1960s. Explains importance of electron microscopy, importance of tilting object, detailed description of this work. AK worked out mathematics of 3-D image reconstruction from 2-D images. Published in 1968. More about papers from 68 - 71. Back to x-ray scanner - explored those methods. Paper published in Nature in 68 - the instrument later patented by Hounsfield. First brain scanner had rotating beam to get 3-dimentional image - basis worked out by AK. AK got Nobel Prize in 1982 for development of crystallographic electron microscopy and elucidation of the structure of nucleic acid protein complexes of biological importance. Explains further about his work More about his work with Caspar in 62 - architecture of spherical viruses and all the various puzzles - refers back to earlier papers in the fifties and how various problems were solved over the years, e.g. building optical apparatus and how it was used.

  • Description

    Nobel Prize-winning chemist Aaron Klug in conversation about his life and work. Klug is most famous for his research into crystallographic electron microscopy.

  • Related links

    Visit this interviewee's page on the 'Voices of Science' web resource

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